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Atherosclerosis - a systemic disease characterized by lipid disorders, accompanied by arterial disease (through the formation of atherosclerotic plaques). Circulation is impaired, due to changes in the arterial walls, accompanied by deposition of cholesterol and certain fractions of lipoproteins.
The disease develops in people over 50 years, although it can develop earlier when exposed to precipitating factors, such as: Obesity Unbalanced diets smoking and alcohol abuse, etc.
The disease is caused by the accumulation of low-density lipoprotein (LDL) and very low density lipoproteins (VLDL) in the intima of blood vessels and muscle musculo-elastic types (aorta, aortic arch arteries, the arteries of extremities). Classification of atherosclerosis
The development process begins with the formation of atheromatous park spots on the surface park of the intima of the arteries. Subsequently, to begin to approach the duty macrophages and leukocytes (leukocyte migration) and in the development of spots begin to form foam cells and as a result of metabolism that develops atherosclerotic plaque. Is plaque prevents normal blood filling body, and as a result developed ischemia and subsequent necrosis. Also, on the surface of platelets may form thrombi that broke away to result in a stroke or infarction.
Clinic in atherosclerosis is characterized by lesions of the relevant body clinic: With the defeat of cerebral atherosclerosis will develop headache, dizziness, frequent fainting When lesions of arteries park observed their coldness, the disappearance of the pulse With the defeat of the mesenteric vessels observed abdominal pain, bloating.
In severe cases, the plaque can rupture and ulcerate. This represents a great danger, as at break of aortic plaque develops park massive bleeding and death is almost always observed.
Should be comprehensive, performed under medical supervision in a hospital or outpatient and include: normalization diet avoiding harmful habits drug therapy: cholestyramine, tsetamifen, linetol, miteonik vitamin park (groups B and D)
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