Cholesterol Blog Archive Atherosclerotic plaque
Atherosclerotic plaque formation significantly stretched in time. Depending on the type of metabolic process can take from a few years to a few decades. Asymptomatic plaque formed just at the time when we "once to see a doctor," we have nothing to be concerned, we have many important and not so important things, and the future seems bright. However, gift baskets pathological-anatomical dissection of American soldiers who died in the late '50s in Vietnam showed that young people aged 20-25 years had the vessels lumen of which is up to 50% was blocked by atherosclerotic plaque. And it's young people! These facts were one of the reasons to get the American scientists to create a national program for the study of atherosclerosis. In the course of this program, as well as studies conducted around the world with varying degrees of intensity, able to decipher the sequence of formation of atherosclerotic plaque. In its simplest form it looks as follows. With increasing content of "bad" LDL cholesterol or change their structure cell of the immune system (macrophages) captures such increased quantities in LDL. Capture modified LDL is not regulated by conventional systems and therefore occurs before the complete destruction of macrophages. As a result, the resulting crystalline cholesterol into the wall of the vessel and forms a so-called "yellow spot." "Macula" is a precursor of atherosclerotic plaque and the beginning of its development, has no significant effect on the passage of blood vessels gift baskets and blood flow to organs. gift baskets In addition to the formation of macular crystalline cholesterol annoying vascular smooth muscle hypertrophy and its causes, which is one of the causes of hypertension. Smooth muscle cells begin to intensively divided. In a subsequent violation of their food leads to degeneration and replacement by connective tissue. Violation of the trophic (food) such tissue leads to its destruction and the formation of atheromatous plaque (atheromatosis in Greek athera - mush). Ulcerated plaques occurs and damaged site formed thrombus. Thrombus in the separation gift baskets occur ischemic organ damage. Later atheromatous plaque begins obizvestvlyatsya (calcified). With the proliferation and a thickening of the postponement of calcium plaque and lumen reduction. Symptoms of atherosclerotic vascular lesions appear when they overlap plaque clearance by 75%. Plaque becomes gift baskets brittle and can crack on crack just formed a blood clot (thrombus). If a blood clot breaks away from the plaque - it may occlude the vessel and disrupt blood flow to the body. As a result, depending on which body disturbed blood flow may develop heart infarcts, bowel ischemic brain damage. Plaque which formed a clot called lethal. It should be noted that cholesterol plays an important role in the formation of "yellow stain", ie in the early stages of atherosclerosis. The magnitude of the already formed plaques he has no significant influence. Therefore, control of blood cholesterol is the most important even before the onset of symptoms of atherosclerosis. Formed in the presence of atherosclerotic plaque in the first place probably goes calcium metabolism. Research in this area is now being conducted. In terms of avoiding potential heart attacks and strokes are advised to take so-called anticoagulants (drugs prevent the formation of a blood clot). According to the results of population studies made recommendations according to which after the age of 40-45 years need to proactively take 1/4 tablet of aspirin every day. Such prevention will reduce the likelihood of thrombus formation and the risk of performing an action "lethal plaque."
Thus, even before the appearance of signs of atherosclerosis (a young age) need to control the level of cholesterol. If you have symptoms of atherosclerosis relevance of this monitoring is greatly reduced. As they say "late drink Borjomi fell off when the kidneys." Although the saying "better late than never" here also suitable. gift baskets Probably in the next decade will be developed and funds decalcified atherosclerotic plaque exposing gift baskets her back development. Currently, however, no such drugs and the only means of combating atherosclerosis is its prevention by keeping blood cholesterol levels in a safe range.
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Atherosclerotic plaque formation significantly stretched in time. Depending on the type of metabolic process can take from a few years to a few decades. Asymptomatic plaque formed just at the time when we "once to see a doctor," we have nothing to be concerned, we have many important and not so important things, and the future seems bright. However, gift baskets pathological-anatomical dissection of American soldiers who died in the late '50s in Vietnam showed that young people aged 20-25 years had the vessels lumen of which is up to 50% was blocked by atherosclerotic plaque. And it's young people! These facts were one of the reasons to get the American scientists to create a national program for the study of atherosclerosis. In the course of this program, as well as studies conducted around the world with varying degrees of intensity, able to decipher the sequence of formation of atherosclerotic plaque. In its simplest form it looks as follows. With increasing content of "bad" LDL cholesterol or change their structure cell of the immune system (macrophages) captures such increased quantities in LDL. Capture modified LDL is not regulated by conventional systems and therefore occurs before the complete destruction of macrophages. As a result, the resulting crystalline cholesterol into the wall of the vessel and forms a so-called "yellow spot." "Macula" is a precursor of atherosclerotic plaque and the beginning of its development, has no significant effect on the passage of blood vessels gift baskets and blood flow to organs. gift baskets In addition to the formation of macular crystalline cholesterol annoying vascular smooth muscle hypertrophy and its causes, which is one of the causes of hypertension. Smooth muscle cells begin to intensively divided. In a subsequent violation of their food leads to degeneration and replacement by connective tissue. Violation of the trophic (food) such tissue leads to its destruction and the formation of atheromatous plaque (atheromatosis in Greek athera - mush). Ulcerated plaques occurs and damaged site formed thrombus. Thrombus in the separation gift baskets occur ischemic organ damage. Later atheromatous plaque begins obizvestvlyatsya (calcified). With the proliferation and a thickening of the postponement of calcium plaque and lumen reduction. Symptoms of atherosclerotic vascular lesions appear when they overlap plaque clearance by 75%. Plaque becomes gift baskets brittle and can crack on crack just formed a blood clot (thrombus). If a blood clot breaks away from the plaque - it may occlude the vessel and disrupt blood flow to the body. As a result, depending on which body disturbed blood flow may develop heart infarcts, bowel ischemic brain damage. Plaque which formed a clot called lethal. It should be noted that cholesterol plays an important role in the formation of "yellow stain", ie in the early stages of atherosclerosis. The magnitude of the already formed plaques he has no significant influence. Therefore, control of blood cholesterol is the most important even before the onset of symptoms of atherosclerosis. Formed in the presence of atherosclerotic plaque in the first place probably goes calcium metabolism. Research in this area is now being conducted. In terms of avoiding potential heart attacks and strokes are advised to take so-called anticoagulants (drugs prevent the formation of a blood clot). According to the results of population studies made recommendations according to which after the age of 40-45 years need to proactively take 1/4 tablet of aspirin every day. Such prevention will reduce the likelihood of thrombus formation and the risk of performing an action "lethal plaque."
Thus, even before the appearance of signs of atherosclerosis (a young age) need to control the level of cholesterol. If you have symptoms of atherosclerosis relevance of this monitoring is greatly reduced. As they say "late drink Borjomi fell off when the kidneys." Although the saying "better late than never" here also suitable. gift baskets Probably in the next decade will be developed and funds decalcified atherosclerotic plaque exposing gift baskets her back development. Currently, however, no such drugs and the only means of combating atherosclerosis is its prevention by keeping blood cholesterol levels in a safe range.
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